Kanker en Curcumin: Deel 2.

Daar is n paar produkte in die Literatuur wat kankerwerende eienskappe bevat. Dit is waarskynlik beter om dit te beskrywe, dat dit kankergenesende eienskappe bevat wat voorkomend gebruik moet word.

Die produk wat hier beskrywe word, is Curcumin. Die aktief in borrie. Met hul bio-opneembare uitdagings en voordele.

Inleiding

Die effektiwiteit, die veilige farmakologiese waarde van curcuminoïede noop mens om die potensiaal te kyk van curcumin as hulpmiddel teen kanker, as anti-oksidant en die ander waardes wat dit as natuurlike plant en middel mag hê teen verskeie siektes.

Die gebruik van borrie, (curcumin is die aktiewe bestanddeel in borrie) word al eeue lank gebruik in die Ayurveda gebruike. In die moderne era is daar vele belangrike studies in die Literatuur wat fokus op die aktief in borrie, naamlik “Curcumin” gedoen.

Borrie word onttrek uit die wortel van die plant “Curcuma longa.” Borrie en of die aktief, curcumin word  nie geredelik deur die liggaam opgeneem nie.

Die waarde van curcumin moet met ‘n “sleutel” in die Biologie vir die liggaam ontsluit word. Hierdie “sleutels” is sekere tipes van vette en olies en enkele alkohole. Waarskynlik is die belangrike “sleutel” is die aktief wat binne swartpeper gevind word, naamlik “Piperine.”

Die aktiewe komponent Curcumin.

Literatuur bevind dat curcumin bepaalde werkinge en of uitkomste het in verskeie belangrike biologiese gebeure in die liggaam. Curcumin se chemiese funksie fokus op “molekulêre teikens,” wat veral vir menslike en dierlike gesondheid belangrik is om te kan inhibeer of dit te moduleer, veral wanneer gevreesde siektes ‘n rol speel.

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Curcumin inhibeer/onderdruk/verander/moduleer die “transkripsie faktore” wat die selgroei van die volgende siektetoestande bevorder.

  • Kanker
  • Artritis
  • Diabetes
  • Hart en hartvatsiektes
  • Crohn se siekte
  • Osteoporose
  • Alzheimers
  • Velkondisies soos psoriase, ens.

Wat is ‘n “Transkripsie Faktor?”

  • Vele molekules of familie van molekules tree op as transkripsie faktore.
  • Transkripsie Faktore word in elke sel van die liggaam gevind.
  • Transkripsie faktore is ook verskillend in verskillende selle.
  • Transkripsie faktore het in die verskillende fases in die ontwikkeling van selle ‘n veranderlike aard en karakter.
  • Transkripsies faktore reguleer ook die boodskappe wat deur die geen in ‘n sel produseer word.

Transkripsie faktore is proteïene wat bind aan spesifieke gene van ‘n sel se DNA. Dit bind veral aan die “promotors” van die sel se funksie, wat dan skadelike funksies kan promoveer. ‘n Promotor is “aktiveerders” in die sel wat funksies van die sel bevorder.

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Verskillende transkripsie faktore is verantwoordelik vir die patrone of die biologiese uitdrukking van spesifieke gene in selle. Transkripsie faktore is verantwoordelik vir die aktivering van die veranderlike gedrag van gene wat in selle mag plaasvind.

Enkeles is;

  • Cycloxygenases of COX COX2, 5-LOX, iNOS
  • Hemeoxygenase-1.”
  • Selproteïne soos Cyclin D1 and p21
  • Cytokines soos TNF, IL-1, IL-6
  • Chemokines
  • Reseptore soos EGFR, HER2 en,
  • Sel oppervlak molekules of “cell adhesion molecules.”

Transkripsie Faktor 1: NF-κB (Nuclear factor kappa-light-chain-enhancer of activated B cells)

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Die NF-κB faktor word in alle tipes selle van mens en dier gevind en, is betrokke by selreaksies wat gestimuleer word deur

  • Stres
  • Sitokinese
  • Vrye radikale
  • Swaarmetale,
  • Ultravioletstraling en irradiasie.
  • Die NF-κB faktor speel ‘n sleutel rol by die regulering van die immuunrespons by infeksies en soorte van inflammasie.

Die verkeerde regulering van die NF-κB faktor in die liggaam word gekoppel aan kanker, inflammatoriese asook outo-immuunsiektes, septiese skok, virale infeksies asook verswakte immuun-ontwikkeling.  Die NF-κB faktor word ook verbind aan verswakte senuweefunksies,  algemene spierverswakking en ook geheueverlies.

Die NF-κB faktor word ook impliseer by skadelike cholesterol wat vorm waar die vorming van gesonde LDL cholesterol beskadig word deur chemiese blootstelling waar vrye radikale induseer word. Die NF-κB faktor word ook geïmpliseer by die skadelike uitwerking van skadelike bakterie en virale antigene.

Transkripsie Faktor 2: (AP-1) of “Aktivering Proteïen 1.”

Aktivering proteïen 1 is ook ‘n transkripsie faktor wat “ geen-uitdrukking” reguleer (hoe gene in die sel reageer) in reaksie van bepaalde stimuli of oorsake, wat ook stres, sitokinese, vrye radikale, swaarmetale, bakteriese en virale antigene insluit.

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AP-1 reguleer ook selprosesse soos

  • differensiasie (wanneer ‘n sel van een tipe sel na ‘n ander verander)
  • proliferasie ( waar ‘n moedersel verdeel en twee dogterselle produseer
  • apoptose (geprogrammeerde selsterftes plaasvind).

Transkripsie Faktor 3: Egr-1 of “Vroeë Groei Reaksie.”

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  • EGR-1 word as ‘n Early growth response” proteïen beskrywe. Ook bekend as Zif268 (zinc finger protein 225) of NGFI-A (nerve growth factor-induced protein A).

 

Transkripsie Faktor 4: Katene (Catenin)

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  • Katene is ‘n groep proteïene wat normaalweg die skakeling tussen selle bevorder en bepaalde funksies uitvoer soos om spesifieke selverbindings mee te bring.
  • Dieselfde faktore wat ‘n rol speel in normale funksionering van selle en hul normale biologiese funksies, soos die afsterwe van selle, die handhawing of balans (homeostase),  herstel en ook groei van selle, dieselfde faktore kan in ‘n negatiewe sin dieselfde rol en funksie vervul by abnormale selgedrag, soos by die vorming van tumors.

Transkripsie Faktor 5: “Peroxisome proliferator-activated receptor” of PPAR

PPAR het verskeie metaboliese funksies in selle en behoort aan ‘n groep van proteïene wat ook estrogeen, Vitamien D, en die hormone van die skildklier insluit. Die familie van PPAR’s  word verteenwoordig deur drie lede, naamlik PPAR-α, PPAR-δ, and PPAR-γ.

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Dit het ‘n komplekse en ook wye verskeidenheid van rolle en in funksies in die liggaam. PPAR-γ transkripsie faktor inhibeer normaalweg die ontstaan en ontwikkeling van skadelike selle en word soos volg aangehaal en beskrywe;

“PPAR-γ activation inhibits the proliferation of malignant cells, including those derived from liposarcoma, breast adenocarcinoma[33] prostate carcinoma, colorectal carcinoma, etc. “

Die PPAR-γ transkripsie faktor kan egter ‘n tweesnydende swaard wees. Dit kan ook vir verskeie redes die vorming van kwaadaardige selle se ontwikkeling bevorder.

Curcumin blok die vorming en formasies van reaktiewe oksidasie in selle.  Curcumin inhibeer ook die ensieme en verskeie prosesse wat inflammasie in die liggaam of selle aktiveer.

Curcumin se oorsprong

Die effektiwiteit, die veilige farmakologiese waarde van curcuminoïede in algemene voorkomende  gesondheidspraktyke,  vereis dat daar weer na die potensiaal van curcumin gekyk word in verskeie siektetoestande soos in die Literatuur opgeteken.

Borrie word gemaak van die wortel (risome) van die Curcuma Longa plant. Van die totale worteloes word sowat 2-5% curcumin geoes. Borrie se bekende geel kleur word vir vele ander gebruike in voedsel en klerebedryf gebruik, maar word in die medisyne as “curcuminoïede” beskrywe.

Dit is reeds in 1842 geïsoleer deur ‘n navorser met die naam van Vogel.

Opneembaarheid van borrie.

Borrie en curcumin se nadeel is dat die “vet” of “oliewaardes” van die molekule prakties onoplosbaar is in water. Die molekulêre of chemiese struktuur van curcumin is C21H20O6. Curcumin in die Chemie staan ook bekend as “Diferuloylmethane.”

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In die “ChEBI Databasis,” (Chemical Entities of Biological Interest) Databasis word borrie of curcumin in vele produkte gebruik. (Die volgende skrywe word in Engels gelaat vir maklike verwysing, indien ‘n leser verdere ondersoek sou wou instel.)

Curcumin has a role as a metabolite, an anti-inflammatory agent, an antineoplastic agent, a hepatoprotective agent, a flavouring agent, a biological pigment, a nutraceutical, an antifungal agent, a dye, a lipoxygenase inhibitor, a ligand, a radical scavenger, a contraceptive drug, an EC 3.5.1.98 (histone deacetylase) inhibitor, an immunomodulator, an iron chelator, a neuroprotective agent, a food colouring, an EC 1.1.1.21 (aldehyde reductase) inhibitor, an EC 1.1.1.25 (shikimate dehydrogenase) inhibitor, an EC 1.1.1.205 (IMP dehydrogenase) inhibitor, an EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone) inhibitor, an EC 1.8.1.9 (thioredoxin reductase) inhibitor and as an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor, a polyphenol, a beta-diketone, an enone, a diarylheptanoid and an aromatic ether.

Curcumin en Kanker

Inleiding

  • Curcumin is ‘n kragtige antioksidant. Dit is ook die vriendelikste deel van die bio-aktiewe gedeelte van borrie.
  • Dit het ook verskeie eienskappe om kolesterol te verlaag.
  • Dit bevat vele “phyto” nutriënte soos curcuminoïede wat kanker op verskeie stadia inhibeer. Dit sluit in die ontstaan van potensiële oorsake van kanker, die ontwikkeling en die bevordering daarvan.
  • Curcumin word beskou as ‘n kragtige “anticarcinogenic compound, wat tumor-ontwikkeling verhoed en onderdruk/inhibeer, (carcinogenesis) en ook “angiogenesis” optree, wat die vorming van nuwe bloedvate wat tumors kan bedien, onderdruk of verhoed.
  • Curcumin het die potensiaal om “mitogen-induced proliferation” van limfosiete te onderdruk.
  • Curcumin onderdruk ook die stimulasie van neutrofiele (witbloedselle) en ook die
  • Die “mutagenesis” van gladde spierselle.

Die navorsing oor hoe dit gebruik kan word, word voorgestel in Afdeling 3.

WAARSKUWING:

  1. MOET NIE BIOPERINE IN ISOLASIE MET ANDER MEDIKASIE OF PRODUKTE GEBRUIK NIE. 
  2. DIT VERSTERK DIE AKTIEF EN KAN TOT VELE TOESTANDE LEI WAT SKADELIK KAN WEES.

 

Pierre van Niekerk

Curcumin en Kanker: Deel 1.

Kroniese Stres en Kortisol: Die oorsake en gevolge

Inleiding

Waarskynlik is stres van soorte, die enkele grootste oorsaak by kanker. Stres het in vele opsigte duisende seekat-tentakels wat in verskeie vorme voorkom. Stres is geen “Engel van die Lig” wat sonder handskoene getakel moet word nie.

Stres in sy vele vorme kan net individueel bestuur word. Dit kan net suksesvol bestuur word as die impak van stres se werklike skade besef word.  Stres mag nooit ligtelik met een of ander pil alleen  onderdruk word nie.

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Pyne en skete

Stressors van soorte, waarvan enkele hier kortliks verduidelik word, manifesteer in vele vorme, waaronder pyne en skete. Die toestand beïnvloed vele kere mense se produktiwiteit, gehalte van lewe, gedagtegang, persoonlikheid en is ook waarskynlik ‘n baie groot rolspeler van stygende mediese kostes en uitgawes.1,2

Pyn van soorte is ook die primêre oorsaak wat veroorsaak dat mense mediese of medisinale intervensie soek om daarvan ontslae te raak. 3,4

Daar is ‘n magdom metodes om kliniese ondersoeke te doen om die oorsake van die verskillende groepe van pyne te vind om te behandel, wat psigologiese toestande insluit. Daar is natuurlik ook nie-pynverwante oorsake van stres wat in die proses van stresbehandeling, korrek geïdentifiseer moet word om behandeling daarvan suksesvol te maak. 5,6

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Stres wat deur pyn veroorsaak word, word vele kere oordryf as lewensgevaarlik. Dit word ook vele kere hanteer asof dit dan in totaal vermy moet word omdat dit lewensgevaarlik is. 2,7,8

Literatuur beweer dat die psigosomatiese toestand by sommige mense die werklike pyntoestand vele kere totaal oordryf. Ook dat die psigiese persepsie en toestand daarvan die herstel proses belemmer en onnodig verleng.

Dit kan veroorsaak dat die persoon sieker word as wat hy/sy werklik is. 2,710

Studies wat die risiko faktore van die onderskeie tipes pyn bestudeer, onderskei tussen 2 tipes of groepe van pyn.

  1. “Muscolosketal Pain” is pyn wat ongemak in die strukture van die liggaam veroorsaak. Strukture soos spiere, bene, ligamente, kraakbeen, rugwerwelkolom en senuwees.
  2. Psigosomatiese Stres is pyne wat veroorsaak word deur vergroting van ‘n situasie, vrees, die siening dat die kleinste gebeurtenis ‘n katastrofe is.

Houding, waardes, vaardigheid

Negatiewe hantering of “coping” 1,2,79  van die lewe en sy gebeurtenisse is ook ‘n belangrike komponent wat fisiese pyn en skete veroorsaak.

Terapeute gebruik verskillende oefening en “Face your Giants” tegnieke om hierdie toestande aan te spreek. 11

Psigosomatiese oorsake en respons tot pyn moet egter in breër verband deur kundiges in hul verskeie velde aangespreek word. Stres beïnvloed die mens se neuro-endokriene stelsel en veroorsaak ‘n wanbalans van hormone.

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Opsommend: Doel van die Skrywe

Begrip en kennis tussen werklike van fisiese pyn en psigologiese pyn, asook die vind van ‘n balans tussen fisiese pyn, psigologiese pyne en die oorsake en invloede van stres, mag dalk ‘n persoon se gehalte van lewe verbeter en hom/haar instaat stel om hul fisiese en geestelike gesondheid beter en veiliger asook gesonder te bestuur.

Die bestuur van stres, die persoonlike hantering daarvan het ‘n natuurlike liggaamlike respons. Hierdie respons speel in die vorming en ontstaan van vele siektes ‘n belangrike rol. Nie net in kanker nie.

Individue speel uiteindelik self ‘n belangrike rol in die ontstaan van hul siektes. Genetiese oorsake is altyd betrokke, asook eksterne faktore wat siektetoestande kan veroorsaak. Dit word nie hier bespreek nie.

Lees gerus hier die Artikel:

rheumotoid_Arthritis

inflammation-atherosclerosis-cancer-obesity-infections-dementia-depression-5-638

Stres Respons: Hipotalamiese-Pituïtêre-Bynierskors (HPA-Axis) en Kortisol

Neurologies funksioneer die mens tussen die “Simpatiese senutoestand (Veg of vlug)” en die Parasimpatiese” senutoestand, (Rus en eet/verteer).

  1. Die Simpatiese Senutoestand
  • Is die veg of vlugtoestand van die liggaam. Die simpatiese toestand of proses bevorder die afbreek van voeding na kleiner partikels. Dit is dus partikels soos lipiede en proteïene, na vetsure, nukleotiede en aminosure.
  • Katabolisme is die “afbreek” aspek van metabolisme.
  • Die simpatiese senutoestand bevorder die kataboliese afbreek van vet en weefsel om glukose te produseer vir energie, bewustheid, motivering, en doelgerigte gedrag. 12
  1. Die Parasimpatiese Senutoestand

Bevorder heling en herstel van weefsel, immuunstelsel op te bou asook anaboliese groei (sintetisering van protoplasma om groei en herstel te stimuleer) om energievlakke te herstel en uithouvermoë uit te bou.12

Wat belangrik is:

Dat ‘n balans gevind word tussen die twee toestande,  die simpatiese en ‘n parasimpatiese toestand, wat van kritiese belang is in die langtermyn fisiese,  en psigologiese gesondheid.

Kortisol

Kortisol is ‘n kritiese kataboliese hormoon wat deur die byniere produseer word13 Dit word periodiek in die liggaam in die oggend geproduseer en verlangsaam gedurende die dag. 14,15

Gedurende die dag handhaaf kortisol bloedglukose en onderdruk ander orgaansisteme om energie te verskaf aan die aktiewe breinfunksies asook al die ander spiere en senuwees.

Kortisol is ‘n baie sterk anti-inflammatoriese hormoon.

  1. In balans keer dit senu en weefselskade wat met inflammasie geassosieer word.16
  2. Kortisol is ‘n belangrike faktor by mens en dier se respons by stres.
  3. By ‘n toestand van skrik en of skok, sal kortisolvlakke skielik verhoog om mens of dier die nodige spieruithouvermoë en ook energie te gee om te veg of te vlug wanneer dit nodig is om te oorleef.13,17
  4. Alhoewel kortisolproduksie baie nodig is in die korttermyn, asook wanneer nodig in gevaar, is langdurige kortisolproduksie baie skadelik langdurig, vir beide geestelike, fisiese en emosionele balans en gesondheid. 1618
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medical illustration showing inflamed, painful joints; Shutterstock ID 173305178; Brand: Nutritional Outlook; LocationProduct: Magazine; Date: 10/16; Purpose: Editoral

Die Akute Stres Respons

‘n Stressor of stresveroorsakende stimulus is enige aksie/toestand/stimulus/rede/oorsaak wat ‘n fisiologiese reaksie in die liggaam veroorsaak wat as stres of angs gedefinieer kan word.

Dit kan vele toestande wees;

  • Fisiese bedreiging tot veiligheid
  • Eise wat die onmoontlike verwag
  • Onsekerheid oor veranderlikes in die omgewing
  • Oorlog en dood
  • Siektetoestande
  • Politieke oorsake
  • Finansieel
  • Werksomstandighede
  • Liefdesteleurstelling
  • Armoede en tekorte aan fisiese vermoëns om te sorg, soos in droogte

Enige toestand of omstandighede wat die moontlike verwagte uitkoms van ‘n verwagting nie waar word nie, kan as ‘n stressor beskou word. ‘n Effek van die stressor wat skadelike nagevolge en effekte op die mens en dier kan hê. 7,19,20

Amigdala

Ongeag of ‘n stressor en of stres stimuli pynverwant of nie pynverwant is nie, soos werkslading, werksverliese, verlies aan respek of agting, lewensmaat, finansies, kanker en of kroniese siektes, die blote wete of denke dat verlies vir ‘n persoon onbeheerbaar is, en nie omkeerbaar nie, kan ‘n negatiewe fisiologiese respons meebring. 1,2,7,20

Literatuur beskrywe dat stressors soos bankrotskap, werkloosheid, verlies aan sosiale status, vrees om iets belangriks te verloor, soos ‘n kind of dier of lewensmaat, die amigdala, ‘n gedeelte van die limbiese gedeelte van die brein. 21 stimuleer en beïnvloed.

  • Die amigdala reageer op vrees en gevare deur die onmiddellike simpatiese respons te stimuleer.
  • Kort daarna sal ‘n neuro-endokriene reaksie gestimuleer word, ‘n natuurlike ingebore respons om die (homeostase) balans in die liggaam te herstel om oorlewing te verseker. 13,15,22,23

Belangrik

Wanpersepsies, wanaangepaste hantering van stressors, onnadenkende wyses asook geloofsoortuiging hoe om sulke stressors te hanteer, kan ‘n oorreaksie veroorsaak en dus ‘n onnodig verhoogde fisiologiese stresrespons wat die reaksietyd tot herstel onnodig kan verleng, asook die pynervaring en belewenis onnodig kan verleng. 20,24,25

Die hantering van pyn as stressor.

‘n Negatiewe siening en ervaring van pyn kan die pynervaring onnodig fisiologies verleng. By die ontstaan van akute vorms van stres, stuur die amigdala boodskappe na die brein om simpatiese senureaksies te aktiveer. Pynervaring stimuleer ook hormone van die byniere (catecholamine), wat onderskeidelik dopamien, “norepinephrine” (oor genoem noradrenalien of noradrenalien) en “epinephrine” wat ook bekend is as adrenalien. 15,26

Kenmerke

Hierdie neuro-oordraagbare hormone se funksies veroorsaak by verhoogde produksie versnelde hartklop, verhoogde bloeddruk, gejaagde of vinnige asemhaling, verhoogde sweetproduksie, vernouing van hartvate en die vergroting van die oog se pupille. 12

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Funksie van verhoogde simpatiese senu-reaksies.

Die simpatiese reaksie op die korttermyn is ten doel om anti-inflammatories te wees. Dit het ten doel om antigene, patogene, vreemde voorwerpe en organismes uit aksie te stel en hul werkinge te inhibeer 13,26,27

Akute stres respons, pynverwant of nie, aktiveer ‘n normale fisiologiese stresrespons. (Korttermyn simpatiese afskeiding van adrenalien, ook genoem “epinepherine” en “norepinepherine,” wat gepaardgaan met die afskeiding van die anti-inflammatoriese hormoon, “kortisol.”

Hantering van die stresrespons, veroorsaak dat die vlakke van adrenalien,  kortisol en  norepinepherine normaliseer.

Wanneer stres vir welke redes verleng, of vir welke redes nie hanteer word nie, selfs kunsmatig en instandgehou word, veroorsaak dit ‘n verlengde afskeiding van kortisol. Die toestand veroorsaak ‘n “fear based memory” van stresvolle stimulasies wat inskop by enige toekomstige stresvolle situasies.

‘n Verlengde of langdurige instandhouding van stres resulteer in ‘n disfunksie van die impak van kortisol op die liggaam. Iets wat niemand wil troetel of handhaaf nie.

Kortisol

Kortisol is ‘n kragtige anti-inflammatoriese hormoon. Die disfunksies van kortisol is legio.26,63

Kortisol in disfunksie resulteer in ongemoduleerde inflammasie. Dit aktiveer ‘n siklus van inflammasie, depressie en fisiese pyn wat op hul beurt ‘n onbeheerbare siklus van ongemoduleerde inflammatoriese stressors en response veroorsaak. Dit weens die disfunksies van kortisol.

Studies wys op ‘n magdom assosiasies met inflammatoriese sitokinese, stresverwante kroniese pyn en “salivary hypocortisolism”. Lees hier en hier en hier. Daar is ook vele bewyse in die Literatuur dat stres bydra tot vele vorme van pyn, omdat pyn ‘n direkte verwantskap het met die inflammatoriese respons15,36

1inflammation

 

Pyn en Inflammasie

Inflammasie produseer vrye radikale, oksidatiewe en nitrosatiewe stres en skade aan gesonde selle43,44.  Die versameling van vrye radikale en gepaardgaande oksidatiewe stres dra by tot aktiewe weefsel degenerering en veroudering.  Osteoporose, miopatie, idiopatie en neuropatie is algemeen erkende manifestasies van inflammasie. Pyn op sy beurt is die fisiese effek van hierdie kondisies. 1316

Om die effek verder te kompliseer, veroorsaak inflammasie dat vergrote gapings in die wande wat dien as “barriers” of beskerming tussen bloed en die brein, asook die wande (lining) wat derminhoudelike in die dermkanaal weerhou om weer in die bloedstroom opgeneem te word.

Dit kompliseer klomp faktore in gesondheid. Omdat die immuunsisteem die skadelike toksienes nie herken as skadelike inhoud vir die liggaam nie. 26 Dit veroorsaak dat ander skadelike bakterie en virusse oor deurgelaat word.

Outo-immuunsisteem afwykings.

  • Inflammasie wat so ontwikkel bevorder hipersensitiwiteit hiervoor wat aanleiding gee tot die vorming van outo-immuunsiektes.
  • Outo-immuunsiektes kan ontstaan weens ongekontroleerde inflammasie wat aan vrye radikale bind, wat hul beurt weer aan gesonde selle bind, wat op hul beurt abnormale selle kan vorm wat kankeragtig word. 64
  • Outo-immuunsiektes is waar die immuunstelsel verward raak. Begin om gesonde selle in die liggaam aan te val as hul as “vyande” van die persoon se gesondheid te beskou. 15,16

Lae kortisolvlakke  

Hierdie toestand word verbind met verswakte algemene gesondheid. Wat op weer met vele ander siektes geassosieer word. 43,64,65.  Lae kortisolvlakke en respons word direk verbind met HIV Vigs of “acquired immunodeficiency syndrome, asook kanker geassosieer. 64

Gedrag, gedragsverandering en kortisol.

‘n Gekondisioneerde aangepaste gedragsrespons (Doelbewuste gedragsverandering by ‘n wanaangepaste psigologiese en of psigosomatiese persepsie dat als in die lewe swaar en moeilik is, ook “lewensbedreigend”), kan bydrae tot normalisering van kortisolafskeiding wat aanleiding sou gee tot pyn en inflammasie in die liggaam.

Die afskeiding van kortisol wat langdurig is, is kronies word en ook skadelik.

Die uitvoering van gedrag het te doen oor hoe kinders grootgemaak word. Waaraan hul blootgestel word. Kinders wat nie aktief grootgemaak word om die uitdagings van die lewe self te hanteer nie, kan waarskynlik kandidate wees versteurde gedragspatrone.

Gedragspatrone wat gevestig word en binne hul biologie ontstaan en in vele siektes kan manifesteer weens kortisolvlakke, wat onwillekeurig die hoofrol word in die hantering van situasies wat deel is van die normale lewe.

Blootstelling, wysheid, insig en die wete dat keuses oor hoe verliese hanteer word, (Victor Frankl) is lewensvaardighede wat al vroeg in almal se lewens beoefen moet word. Opvoeding en gedrag asook die uitlewing van gedrag, is direk verbind met biologiese response in die liggaam.

Vele versteurde gedragspatrone kan hieruit ontstaan. Sommige gedrag kan lei tot haat en woede en vergelding, wyl ander patrone kan lei tot selfbejammering, onderdanigheid, vrese vir die lewe, onsekerheid en ‘n verlamming om te waag en te bang wees om vry te lewe meebring.

Die verlies van ‘n geliefde, ‘n lewensmaat, ‘n troeteldier, werk kan dieselfde liggaamsrespons meebring. Ongeag die oorsaak van die verlies, die rigting van gedrag en die gedragsrespons, kroniese stres en die onvermoë om teleurstellings te hanteer, kan manifesteer in ‘n gevoel van moedeloosheid en een van geen hoop en dit word ‘n belangrike gesondheidsaspek en faktor in die gesondheid van ‘n mens. 19

Die bestuur van verliese en teleurstellings is ‘n kritieke aspek in elke mens se lewe. Dit is een van die belangrikste lewenslesse en lewensvaardighede wat alle mense vroeg in hul lewe moet leer om suksesvol te hanteer.

Word die lewensvaardighede nie aangeleer nie, kan versteurde gedrag ontwikkel in aggressie of dit kan manifesteer in die soek van aandag en selfbejammering wat kan ontwikkel in depressie, omdat belangrike lewensvaardighede om teleurstellings en verliese te oorkom afwesig is. 68

Dit lei na versteurde gedrag, verskeie soorte van disfunksionele kortisolafskeiding, na inflammasie, pyn en siektetoestande wat kan lei na vele outo-immuunsiektes en ook kanker. Literatuur in die algemeen verwys na neuro-endokriene afwykings wat ontstaan weens die disfunksionele afskeiding en uitwerkinge van kortisol. 18,3639

th

Opsommend

Kortisol en stressors van soorte is dus een van die grootste en belangrikste aspekte in kanker en outo-immuunsiektes. Dit kan kortweg so opgesom word;

  • Die bestuur van stressors en kortisol
  • Die bestuur van die gevolge van stressors en kortisol, wat die skadelike gevolge van langdurige afskeiding van kortisol insluit
  • Die rol en gevolge van kortisol in pyn en inflammasie, wat kan lei tot outo-immuunsiektes en kanker.
  • Natuurlike produkte wat in die Literatuur beskrywe is, se doelwitte, gebruike en uitkomstes.
  • Dit word in Afdeling 3 beskrywe.

Pierre van Niekerk

Pierre @ Eco-Health: Poultry Litter Bio-Enzyme

Chemical-free non corrosive poultry litter treatment for incredible ammonia, pathogen and odour control. Increases poultry health by forming a continuously working protective biological barrier.

Substance Challenges in Chicken Houses

Ammonia is a serious and continued challenge for poultry and the farmer. It’s corrosive to equipment and damaging to the environment. Conventional wisdom is to change the acidity of the litter to limit ammonia.

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Ammonia is a volatile compound and above 7.2 PH it acts as a gas with adverse effects. Below 7.2 PH it’s converted into ammonium.

This process fluctuates continually, and as ammonia levels increase costly ventilation must be used, which is not a carbon green solution. Harsh and expensive corrosive chemicals are needed to increase PH in an increasing and difficult cycle.

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Mode of Action:

Eco-Health Poultry Litter Bio-Enzyme takes a novel approach to ammonia by involving:

  • Biological Conversion Approach:

A proprietary microbial consortium targets ammonia and permanently converts it to ammonium nitrate fertilizer.

  • Lignin / Carbon Approach:

Ammonia gas levels increase when there is a lack of carbon in the litter bed. When the amount of carbon is less than that required for converting available nitrogen into protein

Eco-Health Poultry Litter Bio-Enzyme makes better use of the available carbon to eliminate the excess nitrogen as ammonia. It adds considerable carbon in the form of lignin, a crucial factor in reducing ammonia.

  • Organic Acid Ammonia Chelation Approach:

Eco-Health Poultry Litter Bio-Enzyme helps to reduce ammonia through a process called chelation.

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Competitive Exclusion:

Health Challenge:

  • Pathogens and their detrimental effects in the poultry environment are well documented.
  • They are extremely dangerous, and very difficult as well as costly to control.
  • They naturally develop resistance and immunity to substances that harm or kill them, in other words harsh chemicals, disinfectants, sanitizers and antibiotics.
  • They build up immunity and resistance over time and become harder to kill the next time.
  • In this vicious unstoppable cycle extra harsh chemicals and more powerful and costly disinfectants are always needed.

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Eco-Health Poultry Litter Bio-Enzyme Solution:  

  • Eco-Health Poultry Litter Bio-Enzymes are safe and good probiotics which naturally occur in nature and are not genetically modified in any way.
  • In every few drops of Eco-Health Poultry Litter Bio-Enzyme product, there are tens of millions to billions of good bacteria.
  • When they are applied, they quickly go in search of food and space, and rapidly outcompete the bad bacteria for their food source.
  • Eco-Health Poultry Litter Bio-Enzyme rapidly keep on reproducing at an exponential rate and completely colonize the area or system.
  • Ensures in a short period of time that the bad pathogens in the litter starve off and die.
  • An incredible fact is that where conventional disinfectants usually stop working after application, the Eco-Health Poultry Litter Bio-Enzyme process can continue for hours, days and more after application, so the effect of a healthy flock environment is long and lasting.

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Eco-Health Poultry Litter Bio-Enzyme is Non-Corrosive:

  • Corrosion of expensive equipment is a serious problem that ruins the profit of poultry operations.
  • Corrosion can happen anywhere in a poultry operation, and current practices in broiler operations only increase the opportunity for corrosion.
  • Corrosion is simply the deterioration of materials through a chemical reaction with the environmental condition.
  • Perhaps the most noted corrosion occurs with the rusting of iron or other such metals.
  • Corrosion is not confined to just metal as it affects plastics, concrete, wood and other materials.
  • The single most deconstructive chemical created by a poultry operation is ammonia.

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  • Ammonia will always be produced in a poultry house as it is a reaction between manure, moisture, and microbiology.
  • Typically, the higher the humidity of a poultry house the greater ammonia levels become.
  • Ammonia is well noted for its detriments to the welfare of the birds, but we rarely hear about this deterioration of metal components in a poultry house.
  • This deterioration includes valuable fasteners, heaters, walls, ceilings and any other metal object.

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  • Many poultry farmers combat ammonia by applying an acid product for poultry litter treatment.
  • The purpose of acid products is to lower the Ph value of the litter.
  • The ends of the spectrum on the Ph scale are ammonia and acid. A very rudimentary thought would be “Where there is ammonia let’s apply acid to make it neutral”
  • This solution has not been thought out. It would take as much acid as ammonia to make a fair play and truly offset the ammonia.
  • That would be extremely expensive not to mention dangerous.
  • The use of such products leads to elevated acid levels that in turn create an even more corrosive poultry house environment.
  • Products that convert into acid materials lead to groundwater contamination.

normal-chicken-poopEco-Health: Poultry Litter Bio-Enzyme is completely safe and is not corrosive.

It’s made up of entirely organic constituents and poses no problem when contacted with skin or animals. By implementing a complete poultry management system with Eco-Health Poultry Litter Bio-Enzyme, a farmer is extending the life of his equipment among other things and is improving his return on investment.

Long Term Ammonia Control:

  • For long term ammonia control, conventional wisdom has been to spread powerful acid products into the poultry house.
  • The logic is that by making the pH level of the litter low enough, if it’s more acidic, then the ammonium can’t in turn convert into ammonia gas.
  • The faulty rationale in this instance is that the ammonium is still there available.
  • The acid doesn’t do away with it. It just traps the ammonium and delays the inevitable problem.
  • Eventually, the poultry manure itself will raise the pH, and the ammonia problem will return.

Eco-Health Poultry Litter Bio-Enzyme works completely differently to acid treatments.

Eco-Health Poultry Litter Bio-Enzyme beneficial bacteria give the natural process a head starts which break the ammonium down faster than it normally would.

  • A specific strain of bacteria is present to bind the ammonium with nitrogen to make ammonium nitrate which is conventional plant fertilizer.
  • Once bound up as fertilizer, it can’t change back, and ammonia is permanently eliminated.
  • With Eco-Health Poultry Litter Bio-Enzyme, competitive exclusion takes time for a colony to establish, and after a few days’ ammonia levels begin to plummet and one will continue to see low ammonia levels.
  • When dealing with a poultry house that has been previously treated with Eco-Health Poultry Litter Bio-Enzyme ammonia levels will be much lower than a house treated with acid.
  • Adding a fresh application Eco-Health Poultry Litter Bio-Enzyme drastically improves the situation.
  • With repeated use of Eco-Health Poultry Litter Bio-Enzyme ammonia problems are nearly eliminated.

Easy Liquid Application:

Eco-Health: Poultry Litter Bio-Enzyme is an easy to apply liquid treatment.

  • Simply mix our highly concentrated formula with water in a clean pressure sprayer and apply thoroughly on the poultry house floor.
  • Conventional dry bulk products are difficult to handle and are labour intensive. In the time what typically takes a few workers to cover a brood section of a broiler house, an entire house can be covered by one person with Eco-Health Poultry Litter Bio-Enzyme.
  • There is also no need for P.P.E.’s (Personal Protective Equipment).

Application Instructions:

Step 1: Seal the house after the flock is removed to maintain a higher temperature.

Microorganisms are more effective in warmer temperatures. Ventilate before re-entry for service, or if moisture begins to condensate in the house.

Step 2: Immediately after de-caking, and before adding new bedding, apply Eco-Health Poultry Litter Bio-Enzyme at the rate of 1L per 400 square meters. For each 1L of concentrate dilute with 100L of water. After diluting wait 30 minutes before applying.

  • A clean pressure sprayer which has not been previously contaminated by disinfectants must be used. Evenly cover the entire surface of the litter bed with spray.
  • Ideally seal the house for 24 hours after application. Follow the standard ventilation program before and after bird placement.

Product Features:

  • Non-corrosive
  • Keeps litter dry
  • Reduce mortality rates
  • Reduces odour
  • Maintain body heat
  • Reduce litter bugs
  • Reduce condemnation rate
  • Increase feed conversion
  • Increase flock weight
  • Binds ammonia
  • Produces clean air
  • Lowers utility costs
  • Lowers exhaust fan costs
  • Reduces caking in litter
  • Non-toxic
  • Convenient liquid form
  • Easy to apply liquid
  • Less shavings required
  • Applied with conventional spray equipment

Packaging and Storage:

Packaged in 25L drums. Store in a cool, dry place. Shelf life valid for 1 year.

Pierre @ Ecohealth Carbohydrate -Derived Fulvic Acid.

What is Carbohydrate-Derived Fulvic Acid

Carbohydrate-Derived Fulvic Acid (CHD-FA™) is an internationally-patented, safe, non-toxic, water-soluble and heat-stable active ingredient for use in food, health supplements and medicines. It is a new, pure and uniform version of an ancient ingredient from nature – environmental fulvic acid.

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 Ask yourself why people take mud baths? It is because of the healing properties of the humic and fulvic acids in the mud. It is often called ‘Nature’s Miracle Molecule’. It is found in soil and nothing on this planet can grow without it. It is the energy of life. Its medicinal properties are well-known and have been documented over thousands of years.

Environmental fulvic acid is formed over a very long period of time in extremely small amounts by millions of beneficial microbes that work on decaying plant matter. Fulvic acid then works to activate the nutrients within soil so that they can be utilised by the cells of plants.

FulvicTextLike its action in soil, fulvic acid serves as an essential vehicle that carries vitamins and nutrients to the right place in our bodies. Rather than a single molecule, it is a range of organic acids, each one having its own action and purpose and the whole working together.

The patented CHD-FA™ is a unique supramolecular fulvic acid – it has a fixed structure with a range of backbone structures (consistent from batch to batch) working in your body as intended by nature.

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Because of CHD-FA™ being a range of organic plant acids it has a wide range of efficacy. It is a proven anti-inflammatory, antiviral, antimicrobial, antifungal and antioxidant agent whilst assisting with nutritional uptake. The unique invention of CHD-FA™ is to simulate what takes place over many years in nature – in essence fast-tracking the natural process.

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You may ask yourself why only now? Why has fulvic acid not previously been used extensively for healing and better health? The reason for this is evident in the table below:

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Carbohydrate-Derived Fulvic Acid (CHD-FA™)                                                          Environmental Fulvic Acids                                    
Free of heavy metals Contains heavy metals
Free of contaminants Risk of contaminants
Batch to batch consistency proven Batches vary
GMP and FSSC 22000 approved Not GMP approved
Own safety work successfully completed Minimal, if any, safety work
Own efficacy proven in vitro and in vivo                                                                                                    Efficacy relies on anecdotal data and general literature

Carbohydrate-Derived Fulvic (CHD-FA™) has had its OWN safety as well as efficacy work completed at various institutions worldwide. It is produced close to Stellenbosch in a cGMP (License No. 0000001280) and Manufacturing Pharmacy (License No. FY54509) which is also a FSSC 22000-approved facility, making it the ONLY fulvic acid being produced under such strict regulatory conditions and having its own scientifically proven safety as well as efficacy record.

Health and Wellness Benefits

CHD-FA™, being a range of organic acids, has a wide array of healing properties each having its own effect on human health. It is a proven anti-inflammatory, antiviral, anti-microbial, antifungal and antioxidant agent whilst assisting with nutritional uptake.

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General health benefits when taking CHD-FA™ are the following:

  • Helps improve nutritional uptake. Studies have shown that CHD-FA™ increases the uptake of minerals by up to 60% more than normal, supporting good health.
  • CHD-FA™ is a proven chelator making ions more available to the body which is crucial for energy in cells.
  • CHD-FA™ is one of the most effective antioxidants eliminating free radicals, limiting their damage to the membranes of cells, proteins and DNA.
  • CHD-FA™ also assists with gut health because of its properties.
  • Because of the mineral and trace elements in CHD-FA™ it is an excellent natural electrolyte that is able to replace essential micro-elements lost when sweating.
  • The various clinical properties of CHD-FA™ assist in building the immune system.
  • CHD-FA™ with its antioxidant, enhanced nutritional uptake and anti-inflammatory properties helps with chronic fatigue.

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Over and above the attributes mentioned above, CHD-FA™ has the following specific health benefits as has been proven by work done on CHD-FA™:

  • CHD-FA™ is an anti-inflammatory
  • CHD-FA™ is antibacterial and antimicrobial
  • CHD-FA™ is antifungal
  • CHD-FA™ is antiviral

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What benefits can you expect when taking CHD-FA™?

Because of all the properties mentioned above, you can expect the following when you regularly drink CHD-FA™:

  • A stronger immune system which gives you better protection against diseases and infections.
  • Better balanced blood sugar.
  • Renewed energy.
  • Reduced inflammation and free radical damage.
  • Shortened recovery time from muscular and joint pains.
  • Better oxygenation.
  • Cleansing of your body.
  • Lessening of health risks associated with heavy metals.
  • Assists with improved concentration.
  • Assists with increased metabolism.
  • Helps reduce recovery time after exercise.
  • When used topically it kills bacteria, preventing or clearing up infections.

CHD-FA™ and Sport

 The various properties of CHD-FA™ have been described under the Benefits section. It is these benefits which make it so useful to people participating in any type of sport because if fulvic acid is taken regularly over a period of 2–3 months, problems associated with lactic acid and carbon dioxide may be reduced.

 

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CHD-FA™ as a free radical scavenger, antioxidant and anti-inflammatory has the ability to protect muscle cells and thus may reduce the detrimental effects of lactic acid build-up and inflammation. Testimonials have shown that when CHD-FA™ sport supplements are taken, muscle soreness after exercise is decreased and an ability to train for longer is noticed.

Testimonials have shown that when CHD-FA™ supplements are taken for a sufficient time, muscle soreness after exercise is decreased and the ability to train for longer is noticed.

It is vital, especially for athletes, to consume a regular amount of anti-oxidants. Well-known anti-oxidants include vitamins A, C and E, but the complex structure of CHD-FA™ makes it far more powerful an antioxidant than any other nutrient known. This, combined with its anti-inflammatory and chelating properties, make it an ideal supplement to be used when doing sport.

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It is widely known that fulvic acid possesses truly remarkable biological properties. It is these properties which make the use of CHD-FA™ as a supplement for athletes a must because it:

  • Is an anti-inflammatory assisting with inflammatory conditions, speeding up recovery in athletes by repairing damaged tissue.
  • Has chelating properties which increase making minerals more bioavailable, assisting in recovery and reducing stress on kidneys.
  • Reduces stress on energy metabolism during sport and recovery.
  • Reduces the impact of free radicals during and after sport.
  • Provides optimal protection against the increased production of oxidants.
  • Provides a very powerful electrolyte.
  • Restores electrolyte balance essential for optimal muscle function and energy metabolism.

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 SAFETY AND TOXICITY

 CHD-FA™ has its own safety and toxicity work completed to allopathic standards. The safety work on CHD-FA™ can be split into two categories, namely:

  • In vitro and in vivo safety work completed on CHD-FA™
  • Safety in production

In vitro and in vivo safety work concluded

The safety of CHD-FA™ has been proven at certified GLP laboratories locally and internationally over a period of many years and at a cost of millions. This work includes the following (please note that this list is not exhaustive – if additional information is required, please contact us):

  • Bacterial Mutation Assay (Ames test): CHD-FA™ was considered to be non-mutagenic.
  • Micronucleus: The test indicated no genotoxicity for both filtered and unfiltered CHD-FA™ in an in vitro micronucleus assay.
  • BCO2 Evolution Test – Assessment of Ready Biodegradability: This test proved that CHD-FA™ is readily biodegradable under the terms and conditions of OECD Guideline No 301B.
  • Pesticides and pyrogens: Tests indicated that CHD-FA™ contains no pesticides whilst that may be the case with environmental fulvic acids.
  • Peer-reviewed Safety and Proof-of-Concept of CHD-FA™: This published article proves that CHD-FA™ is safe for systemic use at 40 ml twice a day.
  • Peer-reviewed safety in immune-compromised patients: A clinical trial published proves that CHD-FA™ is safe for use even if immunity is compromised.
  • Skin irritation testing performed in Germany.

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Safety in Production

CHD-FA™ is produced in a South African Health Products Regulatory Authority cGMP (License Nr 0000001280) and Manufacturing Pharmacy (License Nr Y54509) as well as FSSC 22000 approved facility.

For any product to be considered safe for use in human consumption, batch-to-batch consistency in production is of paramount importance. In contrast to CHD-FA™, environmental fulvic acid varies from batch to batch as it is impossible to ensure consistency.

CHD-FA™ however is a unique fulvic acid being a supramolecule – it has a fixed structure with a range of backbone structures that has been proven to be consistent from batch to batch using the following methods:

  • FTIR
  • MALDI-TOF MS
  • LC-MS
  • NMR
  • GC-MS

To ensure safety and consistency, each batch of CHD-FA™ manufactured has to pass standards as have been set up and validated. The release parameters and test specifications are as below:

  • Appearance: Visual inspection
  • pH: pH Meter <USP 38>
  • Specific Gravity: Hydrometer <USP 38>
  • Electro Conductivity: EC Meter <USP 38>
  • Identification by FTIR <Ph. Eur. Method 2.2.24>
  • Anti-Microbial Efficacy Staphylococcus Aureus total kill
  • Concentration: University of Pretoria-validated concentration method
  • Total Organic & Inorganic Impurities: Gravimetric filtration <EPA-NPDES>
  • Volatile Organic Impurities: Gravimetric filtration <EPA-NPDES>
  • Elemental impurities
  • Cd – Cadmium ICP-OES <Mals 6.4>
  • Pb – Lead ICP-OES <Mals 6.4>
  • As – Arsenic ICP-OES <Mals 6.4>
  • Hg- Mercury ICP-OES <Mals 6.4>
  • Co – Cobalt ICP-OES <Mals 6.4>
  • V – Vanadium ICP-OES <Mals 6.4>
  • Ni – Nickel ICP-OES <Mals 6.4>
  • Nitrate & Nitrite: Lachatte Flow Injector Analyser <UA EPA 353.3 >
  • Microbial Analyses: <USP 38>  & <BP 2007>
  • TAMC
  • TYMC
  • Bile tolerance gram neg bacteria
  • Salmonella spp
  • Escherichia coli
  • Aureus

Research/Efficacy on CHD-FA™

The medicinal uses of humic substances and fulvic acid have been known for many years. Medicinal products containing humic and fulvic acids with therapeutic indications for inflammation, bacterial infections, allergies, arthritis, rheumatism and various other conditions are freely available. CHD-FA™ is free of heavy metals and environmental pollutants and safe for pharmaceutical interventions. CHD-FA™ has anti-inflammatory, antibacterial, antifungal, antiviral and antioxidant properties.

It has a supramolecular structure that is characterised by twenty-four principal backbone structures embedded in CHD-FA™. The backbone structures are associated with each other and with the parent structure through intermolecular bonding to form a supramolecular structure. It is all these backbone structures (consistent from batch to batch) that give CHD-FA™ its wide range of efficacy. Three examples of these 24 backbone structures, each with their own medicinal properties, are:

  • Malic acid: Anti-inflammatory; antibacterial; antifungal; antiviral; antioxidant.
  • Tartaric acid: Anti-inflammatory; antibacterial.
  • Acetyl salicylic acid/aspirin: Anti-inflammatory; antibacterial; antifungal.

Specific research completed on CHD-FA™

Over R50 million has been spent on research work specifically on CHD-FA™. The purpose of this was to not solely rely on anecdotal data and general information but to ensure whatever efficacy is claimed in regards to CHD-FA™, there is data to support it. The studies mentioned below under each condition are just some of the studies completed on CHD-FA™ -there are many more. Please contact us if more information on the studies mentioned below or any additional studies that have been done if required.

  • Anti-inflammatory

 Many conditions in the human body are caused by inflammation. CHD-FA™ with its known anti-inflammatory properties will assist with these conditions. The following studies have been successfully completed:

  • CHD-FA™ inhibits Carrageen-induced inflammation and enhances wound healing. This peer-reviewed, published study conducted at the University of Pretoria indicated that CHD-FA™ has its anti-inflammatory effect by neutralising free radicals. The rate of reduction in the inflammation as a result of ingesting CHD-FA™ is equivalent to that of Indomethacin, a registered anti-inflammatory often used.
  • Phase 1 clinical study of the acute and sub-acute safety and proof of concept efficacy in humans. This peer-reviewed, published study also proved that CHD-FA™ acts as an anti-inflammatory.
  • Inflammatory efficacy of CHD-FA™ in an in vitro whole blood assay (human). The conclusion of this study done at Washington Biotechnology was that CHD-FA™ is a potent anti-inflammatory agent comparable to Dexamethasone.
  • In a randomized, parallel-group, double-blind, controlled study to evaluate the efficacy and safety of CHD-FA™ in the topical treatment of eczema, which has been peer-reviewed and published, it was found that CHD-FA™ in a cream formulation successfully improved eczema.

 Antibacterial

Bacterial and microbial infections, both systemic as well as topical, are a major health issue worldwide. Furthermore, antibiotic overuse, as well as not completing prescribed courses of antibiotics, has created a generation of resistant bacteria that, once they have invaded our bodies makes treatment very difficult. Studies at various institutions around the globe found that CHD-FA™ was successful in not only killing a wide variety of organisms, but also has the following effects:

  • Works synergistically with other medicines.
  • Is effective against a wide variety of resistant bacteria.

Antibacterial studies on CHD-FA™, including peer-reviewed and published articles:

  • CHD-FA™ is a highly-promising topical agent to enhance healing of wounds infected with drug-resistant pathogens. This peer-reviewed and published work was done at the Public Health Research Institute, Rutgers-New Jersey Medical School. The study proved that CHD-FA™ is effective against the ‘super-bug’, methicillin-resistant Staphylococcus aureus, a powerful microbe that has become of major concern worldwide.
  • Biological properties of CHD-FA™ as a potential novel therapy for the management of oral biofilm infections. This study conducted at the world-famous Glasgow Dental School, School of Medicines, was peer-reviewed and published, and concluded that CHD-FA™ exhibits broad-spectrum antimicrobial activity against orally-relevant biofilm organisms.
  • Synergistic effect of CHD-FA™. The results of this study conducted at the University of Pretoria showed that CHD-FA™ has antimicrobial activity against Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli, Pseudomonas aeruginosa and Candida albicans. The antimicrobial spectrum of CHD-FA™ compares favourably with that of currently-prescribed antibiotics and acts synergistically with oxacillin (methicillin) and gentamicin. A Gram stain of albicans grown in the presence of CHD-FA™ showed rounded, enlarged, non-dividing bodies indicating that this product acts on the cell wall of microorganisms.
  • Assessment of the in vitro efficacy of CHD-FA ± Oxacillin following several passages in methicillin-resistant Staphylococcus aureus (EMRSA16). This study at Euprotec in the UK indicated that there is no resistance build-up by CHD-FA™.
  • Determination of the in vitro efficacy of CHD-FA™ against multidrug-resistant Enterobacteriaceae and Mycobacteria. The study concluded:
    • CHD-FA™ was effective against NDM-1, KPC and ESBL positive Klebsiella pneumonia and multi-resistant coli strains with a 100% MIC value of 0.06-0.12%.
    • CHD-FA™ was highly effective against multi-resistant Gram negative bacilli including NDM-1 positive strains. CHD-FA was also highly effective against Mycobacterium smegmatis. All organisms were inhibited using ≤0.12% of CHD-FA™.
  • Antiviral

Viruses are microscopic organisms that replicate within the cells of animals, plants and humans and subsequently cause disease. Such diseases can range from the common cold and influenza to Epstein Barr’s disease, herpes and hepatitis, to name but a few.

An in vitro study performed at the University of Pretoria showed CHD-FA™ to be fast and effective in managing feline herpes.

In vitro work was also done at Virologic in the USA against HIV strains, showing efficacy.

  • Antifungal

 Not all fungi are beneficial. Some are toxic and often cause diseases that can be both uncomfortable and dangerous. Examples include: aspergillus (can cause cancer); zygomycetes (can cause serious external skin infections and internal infections along the gastrointestinal tract); and Candida, of which there are many species with the most common one causing vaginal infections. As with many strains of bacteria, many Candida species are resistant to drugs.

A wide range of studies were performed on CHD-FA™ as an anti-fungal agent:

  • Studies carried out at Fungiscope in Germany showed that resistant Candida strains tested were inhibited by CHD-FA™.
  • Assessment of the in vivo efficacy of CHD-FA™ in a murine model of disseminated Candidiasis. This study done at Euprotec in the UK proved that CHD-FA™ is effective in vivo against Candida albicans on its own or in combination with other medicines such as Fluconazole.
  • Assessment of the in vitro efficacy of CHD-FA™ against malassezia and dermatophyte This study done at Euprotec in the UK proved that CHD-FA™:
    • inhibits the growth of Malassezia dermatis, Malassezia furfur and Malassezia globosa when used as a 0.125% solution at its native pH of 2.1 in vitro.
    • inhibits the growth of all dermatophyte strains tested, except Microsporum canis, when used as a 0.2-0.4% solution.
  • Immune Support

Because of its anti-oxidant as well as chelating and other properties such as enhanced nutritional uptake as discussed, CHD-FA™ is effective in supporting a stronger immune system.

  • Anti-Diabetic

Diabetes is a disease affecting millions of people. Because of the various healing properties of CHD-FA™, an in vivo study was conducted at the Medical Research Institute and the outcome was:

The solutions tested significantly enhanced glucose uptake both in the C2C12 muscle and Chang liver cells. The increase in the glucose uptake was comparable to that of metformin, an established anti-diabetic agent.

  • Antioxidant

The antioxidant properties are well-documented in general literature such as the article in the Journal of Food, Agriculture & Environment Vol. 9 (3&4): 123 – 127 (2011). Additional testing has also been done on CHD-FA™ confirming its excellent anti-oxidant properties.

The summary of work done at University of Pretoria concluded: “it has been shown that CHD-FA™ possesses some antioxidant properties in vitro.  This property suggests that this product may be an effective immunomodulator for the treatment of diseases associated with an overproduction of reactive oxidants by human phagocytes.”

  •  Nutritional Uptake

CHD-FA™ assist in nutritional uptake as has been proven by a study at the University of Pretoria. From the study it is clear that CHD-FA™ will assist in the nutritional uptake of various minerals.

  •  Preservative

Because of the antibacterial, antimicrobial and antifungal properties of CHD-FA™, it essentially acts as its own preservative in the various products. The preservative efficacy report by SWIFT SILLIKER confirms the preservative properties of CHD-FA™.

Production Standards and Certifications

  • South African Health Products Regulatory Authority (SAHPRA)

CHD-FA™ is produced and finished products packed in a SAHPRA cGMP (License No. 0000001280) and Manufacturing Pharmacy (License No. FY54509) Facility.

The staff component consists of highly-trained individuals in the positions of Responsible Pharmacist, Production Pharmacist, Operational Manager and Procurement as well as Financial Manager. The site has a Site Master File and full Quality Manual ensuring GMP compliance.

  • FSSC 22000

CHD-FA™ production and packaging of final products is also FSSC 22000 approved. The FSSC 22000 Food Safety System Certification provides a framework for effectively managing an organization’s food safety responsibilities. FSSC 22000 is fully recognized by the Global Food Safety Initiative (GFSI) and is based on existing ISO Standards.

  • FDA registration

The certificate affirms that Fulvimed (Pty) Ltd is registered with the U.S. Food and Drug Administration pursuant to the Federal Food Drug and Cosmetic Act,

  • South African Bureau of Standards (SABS)

The facility is audited and certified by the SABS under SANS 1828.

  • Organic Certification

CHD-FA is also certified organic by ECOCERT. This certification is both for NOP           (USDA organic regulations, 7 CFR Part 205) as well as EOS (meets the  requirements laid down in the ECOCERT ORGANIC STANDARD recognized as    equivalent with the provisions of regulation (EC) No 834/2007).

  • HALAAL

CHD-FA™ is Halaal-approved, as well as a wide variety of the products it is                            formulated and packed in.

PRODUCTS

The wide-ranging efficacy of CHD-FA™ makes it ideal for use in an extensive variety of products, as supported by the work done on CHD-FA™ and knowledge about fulvic acid in the public domain.

 

 

Oxynated Olive Oil Balm

Pierre @ Eco Health Oxynated Olive Oil.

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Introduction

Oxynated Olive Oil cannot be considered a pharmaceutical drug.

  • It is developed to be a skincare product for various external treatments and topical uses on suitable sensitive skins.
  • Oxynated Olive Oil consists of ozone and pure organically produced olive oil.
  • Oxynated Olive Oil Does not contain parabens, phthalates, phenoxyethanols, colorants or fragrances.
  • And it is lastly, proudly not tested on animals.

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A short History of Ozone Oil

Nikola Tesla (in 1900) began marketing an ozonated olive oil to medical doctors in the 1900’s.  Tesla is known as one of the most influential scientists the world has ever seen. When Albert Einstein was asked a tricky question about who the cleverest man on earth is, his answer was politely.

“I don’t know. You have to ask Nicola Tesla”

Nikola Tesla created his ozonated oil by bubbling ozone through pure olive oil in the presence of a magnetic field for eight weeks.

By 1904, ozonated olive oil, also known as “Glycozone”, began appearing in medical literature, such as “The Medical Uses of Hydrozone and Glycozone”, 9th Edition, by New York Chemist Charles Marchland.

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What is Oxynated Olive Oil Balm? 

Oxynated Olive Oil Balm is produced when ozone gas is bubbled through pure cold press virgin olive oil. The bubbling of the ozone through pure virgin olive oil, is a 24/7 continuous process.

The production of one batch of Oxynated Olive Oil last between 4- 6 weeks. During this time the olive oil will turn and change to a soft “off-white” paste.

What is ozone?

  • Ozone is an unstable, but highly beneficial molecule.
  • It’s the tri-atomic form of oxygen
  • Normal oxygen consists of two atoms (O2).
  • Ozone consist of three (3) oxygen atoms (O3).

How does Oxynated Olive Balm function.

  • Ozone is a gas with the chemical formula O3.
  • It is the allotropic form of oxygen (O2), meaning that it is “oxygen in its most active state”.
  • Ozone gas is naturally found in the environment. It well known for the “Gap in the Ozone layer”.
  • The ozone layer protects the planet from the sun’s ultraviolet radiation.

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  • Ozone’s main feature is its incredible ability to purify, its functional ability to eliminate organic compounds, including all known bacteria, fungi and viruses successfully.
  • When ozone is applied directly onto bacteria, fungi and viruses, ozone has an immediate eliminating effect on the organism.
  • The only residue that Oxynated Olive Oil leaves behind, is pure oxygen.
  • This makes Oxynated Olive Oil an extremely effective natural germicide agent.

How does Ozone react with Olive Oil?

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  • With pure virgin olive oil, the ozone reacts with the fatty acids in the olive oil under controlled reaction conditions.
  • This process creates among other compounds, multiple peroxide species such as lipoperoxides, ozonides, aldehydes and ketones.

Multiple studies refer to the synergy that is created between the ozone and olive oil. These studies explain the vast benefits of the molecular structure of ozonated olive oil, with specific reference to the beneficial values it offers.

Not all ozonated oils are equal

Do not ever be misled. Not all ozonated oils are equal.

The quality and functional properties of ozonated olive oil depends on the raw material used (cold press pure virgin olive oil), as well as the quality of the “cold press” manufacturing process.

Ozone is an unstable gas.

  • It does not want to stay in a “tri-atomic” state.
  • It is therefore important to be held in check by other able molecular bindings.
  • Ozone will break down from O3 to O2 to O1 within 20 minutes at atmospheric pressure.

The Importance of the O1 breakdown

  • O1 is called a “singlet oxygen atom”.
  • It is HIGHLY REACTIVE with just about any substance.
  • It will react with almost any organism or substance that should not be in the human body (i.e. viruses, bacteria, fungi, etc.).
  • It is widely in acknowledged in Literature as a “Universal cleansing agent”.

Why Olive Oil? 

 

  • Literature claims that olive oil contains large amounts of “antioxidants.”
  • Apart from its beneficial fatty acids, olive oil also contains modest amounts of vitamins E and K.
  • These antioxidants are biologically active and may reduce the risk of chronic diseases (6, 7).

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  • Olive oil is known to fight inflammation.
  • Olive oil also protects blood cholesterol from oxidation
  • Added to this, is it is well known to lower the risk of heart diseases. (8, 9) in its pure virgin form.

Multiple studies have shown that the combination of oil and ozone has a synergistic effect, highly beneficial for skin health.

  • The O1 factor will protect the skin against external aggressors and the damaging effects of airborne and other harmful environmental free radicals.
  • It will also destroy foreign microorganisms not does not belong in the body.
  • Olive Oil is deeply moisturizing and nourishing, while olive oil purifies, regenerate and helps in the healing processes of the skin.
  • Oxynated Olive Oil improves cellular metabolism. It strengthens the natural anti-inflammatory abilities of the immune system.
  • Oxynated Olive Oil will improve blood circulation, causing ulcers and or severe skin conditions such as dry skin conditions. Especially with elder people and or people constraint to wheelchairs. (See the various uses that follows).
  • The O1- Ozone factor will stop the production of germs present in some skin conditions, such as acne, seborrhea, skin lesions, redness, etc.
  • Ozonated Olive Oil might also be a good alternative to consider as natural treatment, rather than the use of corticosteroid creams.

Does ozone kills good bacteria too?

  • It doesn’t really matter how much and how fast you kill viruses and or fungi or bacteria.
  • If you do not protect your healthy cells from re- infection,  you will never eliminate the cause of illness effectively.
  • It is therefore most important to protect your healthy cells and prevent viruses and bacteria to use these cells from replicating.

This is one of the wonderful side effects ozone provides.

  • Ozone facilitates the Krebs’s cycle by improving the oxidative carboxylation of pyruvate and promoting the synthesis of ATP.
  • There is also an increase in antioxidant enzymes that act as free radical scavengers (such as glutathione peroxidase, catalase and superoxide dismutase). (Ciborowski, Lipska, Godzien, et al., 2012)
  • With the increased protection of healthy cells that are surrounded by protective enzymes, re- infection is reduced to the minimum.

www.o3academy.com/does-ozone-kill-good-bacteria-too/

Conclusion:

  • Oxynated Olive Oil Balm is therefore a valuable medium or vehicle to enrich with powerful “reactive oxygen,” to address the effects of harmful microorganisms.
  • The “O1” singlet Ozonated Olive Oil will actively destroy fungi, parasites, bacteria and spores found on the skin.

Oxynated Olive Oil might also be very beneficial in the following conditions:

  • Diaper rash

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  • Redness

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  • Skin irritations

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  • Dermatitis

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  • Poor blood circulation

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  • Scrapes

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  • Rashes

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  • Skin dryness

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  • Herpes

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  • Vaginal conditions

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  • Anal itching, inflammation and irritation, hemorrhoids

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  • Intimate feminine care

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  • Cuts
  • Burns

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  • Psoriasis

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  • Eczema

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  • Cold sores

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  • Anal fistulas

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  • Seborrheic dermatitis

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  • Ringworm

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  • Athlete’s foot

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  • Foot and toenail fungus
  • Poison oak or ivy

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  • Bee stings
  • Bug bites
  • Bruises
  • Ozonated Olive balm is nowadays used in alternative dentistry, healing abscesses of the gum, periodontal pockets and gingivitis.

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  • Ozonated Olive Oil might be beneficial with skin problems associated with persons with reduced mobility, such as the elderly with diaper rash, ulcers, herpes and bedsores.

Oxynated Olive Oil Skin in conclusion

  • Is a germicide power against bacteria, viruses and fungi
  • Is an anti-inflammatory and antioxidant balm
  • Is actively stimulates the internal or endogenous antioxidant system in the skin
  • Proves to have immune-stimulant properties, as well as an exceptional functional ability to repair and heal tissues
  • It proves to have numerous moisturizing and nourishing abilities
  • It is extremely efficient in destroying external free radical aggressors
  • It will improve and increase functional cell metabolism.
  • Through ozone’s anti-inflammatory properties, it will reduce pain as well as swelling.

Oxynated Olive Oil: Diaper rash, skincare, bed sores, ulcers, etc.

Example 1. There are various causes of diaper rush

  • Baby skin is a delicate fragile organ. The diaper area is expose to faeces, urine, humidity and poor ventilation.
  • The lower abdomen is susceptible to the proliferation of pathogenic microorganisms, that cause inflammation, (bacteria, viruses, spores, fungi) reddening rash, pain and sores.
  • Many children are affected by seborrheic dermatitis, atopic eczema or psoriasis.
  • Not only children, impaired people in wheelchairs as well as the elderly in bed with sensitive skin types, will show signs of rash and irritation.
  • Exposure to these harmful pathogenic organisms can complicate skin conditions.
  • We can therefore except that a baby’s body (also the the impaired and the elderly) is exposed to pathogenic organisms that might be harmful to their skin.

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Diaper rash is known as an “Irritation of the skin under the diaper”.

Diaper rash appears as a red patch with well-delimited borders. Diaper rash can be extremely painful when touched, also depending on its severity.

The redness or red patches also tends to get further irritated because of diapers, creams, fabrics, washing powders, poor quality soaps and fabric softeners.

Varying factors play cause inflamed skin conditions

  • Humidity, and the lack of air flow and intense rubbing.
  • Ammonia produced in urine.
  • Irritants found in faeces, especially when acidic, as is the case of diarrhoea.
  • Products used to wash linen diapers.
  • Cleaning and the excessive use of cosmetic products. 

Example 2: Oxynated Olive Oil and diabetic foot

Oxynated Olive Oil moisturizes, nourishes, purifies and heals the skin

  • Feet is perhaps the most mistreated part of our body. It must withstand many and various external aggressors during a person’s entire lifetime.
  • Feet bear weight, endure wrong footwear, get hot and sweaty, get tired, dirty, compressed, dry out, catch fungal infections, etc.

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There are approximately more than 366 million people with diabetes worldwide today. Among the many complications of this illness, skin related problems are very dominant.

“Diabetic foot” is serious condition that needs special treatment and preventative care.

Oxynated Olive Oil in diabetic skin

Oxynated Olive is an ideal product for caring and protecting the skin.

The skin is also the largest organ in the body. People who suffers from diabetes and blood sugar levels, undergo extreme spikes because they suffer a lack of insulin secretion, not generated by the pancreas.

Sugar level abnormalities, cause the loss of sensation especially in peoples lower body and extremities, in particular their feet. This condition cause damage to blood vessels, resulting in numerous ulcers.

Diabetes is very instrumental in infections and amputations.

Dry feet and cracking heels (Nondiabetic)
Many people suffer common foot problems such as dryness, flaking, cracked heels, swelling, ulcers, sores, scars, fungi, etc.

  • Oxynated Olive Oil will protect and even spoil feet, providing them with the protection, moisture and nutrition that they need.
  • In addition, Oxynated Olive Oil is anti-inflammatory and will combat swelling directly.
  • Oxynated Olive Oil is also highly recommended for women who wear high heels on a continuous basis.
  • Oxynated Olive Oil has germicide abilities that will eliminate the causes of dryness, flaking, cracked heels, swelling, ulcers, sores, scars, fungi without any side effects.
  • In addition, Oxynated Olive Oil has significant healing properties in relieving, soothing and repairing the skin, following the appearance of blisters or ulcers.
  • Oxynated Olive Oil will assist in diabetic skin repair and cellular metabolism, by activating the micro-circulation of blood capillary networks.

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Example 3: Bedsores and skin ulcers

Oxynated Olive Oil will treat areas on the body that is prone to turn into bedsores and ulcers.

Oxynated Olive Oil is a very useful product for those who are bedridden, or in a wheelchair. It will be extremely helpful to people who has poor blood circulation or diabetes.

Oxynated Olive Oil activates the micro-circulation of blood, the capillary networks of the body and cellular metabolism.

The main cause of bedsores is the lack of blood circulation and immobility.

Impaired people spend much to long time in the same passive position.

That interrupts;

  • their normal blood flow
  • resulting in cell death
  • resulting in poor oxygen flow to cells
  • poor discharge of Carbon dioxide or CO₂ from the cells
  • Oxynated Olive Oil will destroy concentration of various free radicals in wounds, and or places which leads to redness, toxins, toxic concentrations, irritations in wounds and bedsores.

Elderly people are at the highest risk of developing bedsores.

But that includes bedridden patients and disabled people with reduced mobility. Wheelchairs will always increase various disorders,

Bedsores can also be caused by other factors;

  • poor nutrition
  • low levels of magnesium
  • stress
  • humidity
  • urine and fecal drops
  • any acquired skin sensitivity.

Oxynated Olive Oil moisturizes, nourishes, purifies and heals the skin through the synergistic effect of organic extra virgin olive oil, and the active O1 ozone molecule, as described.

Example 4: Oxynated Olive Oil and feminine hygiene

Oxynated Olive Oil will sooth irritations associated with hair removal, irritations in and at intimate areas and will also improve circulation in the lower abdominal area, legs and foot care

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Women do have parts of extreme sensitive skin, that is constantly exposed to external aggressors, various types of bacteria and harmful microorganisms, the origins of infections, irritations, dehydration as well as skin dryness.

Women (men to) are also exposed to harmful external aggressors

  • Air-borne bacteria and microorganisms that cause infections, irritation, dehydration, dryness, and acne.
  • The weather plays a significant role in skin conditions
  • Cheap, fake or inappropriate harmful products contaminate the skin itself.
  • Abrupt temperature changes cause facial skin to feel tight, dry, neglected, flaky, etc.

All these external factors cause a rupture in the natural lipid barrier on the skin’s surface. It allows natural moisturizing substances in our skin to evaporate that results into dryness.

  • Oxynated Olive Oil will immediately combat skin dryness, giving the skin the moisture and nutrition that it needs.
  • Oxynated Olive Oil applied at night will help to prevent the appearance of annoying pimples, blackheads and blotches in young children.

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Example 5: Hair removal
Hair removal is associated with rashes, reddening and irritation. Waxing, shaving and conventional diode laser hair removal are serious aggressors.

  • Oxynated Olive Oil is recommended for use directly on the damaged skin as a moisturizer, purifier and anti-inflammatory agent before and after hair removal. This will help to reduce stinging, purify the skin and prevent the appearance of future irritation.
  • Oxynated Olive Oil is highly recommended for use on the most sensitive areas of the body. Areas that rash and inflame the most during hair removal, such as the armpits, soft skin and or shaved intimate areas.

Oxynated Olive Oil and Intimate care
Many women are faced with multiple factors that can cause conditions of personal private harm.

Candida aureus and Candida albicans are associated with irritation, various infections and or the spread of spores of associated fungi.

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It must be noted;

A lack of proper understanding and knowledge of the importance of intimate health care, can result in the appearance of various harmful pathogenic micro-organisms causing  infections.

  • it is harmful microorganisms character to appear with irritating effects in the most intimate female areas.
  • Many times, with infections, the vaginal area became associated with unpleasant smells.
  • It is in general, an unhealthy situation that effects women’s state of mind, interpersonal relations and sexual activities and personal well-being.
  • There are numerous products for feminine care on the market. Their content tends many times to be very harsh and acidic.
  • Many products also alter the very important safety barrier and balance of vaginal pH.
  • Good bacteria in the vaginal area ensures vaginal health and will help to protect and destroy harmful bacteria that enters the vaginal area.
  • Certain medications can cause a reduction in pH-defenses
  • That situation is to the detriment of women’s sexual health, intimacy as well as sexual well-being.

It is well known;

  • That certain fabrics, such as lace in intimate areas, can cause irritation and or burning.
  • Detergents and fabric softeners with a high chemical content can also trigger allergies and irritation.
  • Pubic lice can be a problem to.
  • External allergens such as dust, poor personal health care, careless sexual activities as well as other allergens can cause irritations and allergies.

Oxynated Olive Oil is highly recommended for these conditions.

Oxynated Olive Oil will help to prevent the appearance of pathogenic agents to house themselves in the vaginal area.

It will successfully do so through its germicidal properties. It will also moisturize and protect the infected skin, destroy the bacteria en repair the damaged skin.

Example 6: Circulation and varicose veins (Oxynated Olive Oil and Fulvic Acid)
Varicose veins are dilated and unpleasant-looking surface veins that appear under the skin. They tend to be swollen vessels caused by poor blood circulation.

That is due to a lack of adequate oxygen.

Women are especially predisposed to varicose veins. In many circumstances is is caused by unhealthy habits;

  • Smoking is a serious culprit.
  • A lack of exercise
  • Not eating a healthy diet.
  • Sometimes they can be aggravated during certain stages of pregnancy due to the need to rest.

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It is impossible to prevent their appearance. But, with knowledge it can be avoided by having an active plan to improve movement and blood circulation.

Oxynated Olive Oil, with Fulvic Acid can fight varicose veins as the effects of ozone and Fulvic release oxygen, which helps to oxygenate the blood and improve blood flow.

In addition, it might reduce the visibility of these veins, with Oxynated Olive Oil and Fulvic Acid,  through their abilities to send oxygen to the smallest capillaries in the skin, which very few other products manage to reach.

Example 7: Oxynated Olive Oil, haemorrhoids, anal irritation and itch

  • Haemorrhoids are produced when the veins in the area below the rectum, or in the anus, become excessively dilated, turning the situation into a sort of varicose vein.
  • These dilation’s can be painful, itchy, bloody and burning.
  • Relief from haemorrhoids can be obtained by correcting the factors that aggravate them as much as possible.
  • A dedicated diet, high in fibre and liquids, is recommended to avoid constipation.
  • Haemorrhoids requires a person to avoid alcohol, spicy foods and coffee and a regular low-intensity exercise, such as walking or swimming.

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Oxynated Olive Oil will address the unpleasant symptoms caused by haemorrhoids and any other type of anal irritation, inflammation or itch. Oxynated Olive Oil have a synergistic effect that fights inflammation and irritation, improves metabolism and purifies and lubricates the area, thus providing haemorrhoid relief.

Oxynated Olive Oil also protects and repairing sensitive skin, which makes it very effective for perianal dermatitis or any other types of anal irritation, burning, itch or more continue.

Oxynated Olive Oil not only address the issues associated by haemorrhoids, but also conditions caused by constipation, diarrhoea, acidic feces, anal sex, allergies to soap and or poor quality toilet paper.

Pierre van Niekerk ©

Pyn en Inflammasie II

Verstaan Pyn en Bestuur jou Chroniese Inflammasie natuurlik.

Wat is Inflammasie?

Inflammasie is ‘n kondisie waar jou liggaam teen iets veg en baklei. Om die virus, bakterie, fungi of wat dit ook al is, ter wille van jou algehele gesondheid te onderdruk. Inflammasie kan ook ontstaan weens kneusplekke en beserings. Inflammasie kan ook ontstaan weens voedsel en bymiddels wat ons inneem, soos suiker.

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Inflammasie sneller jou Immuunsisteem om teen die ongewenste vreemde organisme op te tree en dit te vernietig op vele interessante biologiese wyses.

Hierdie reaksie

  • Sluit die vrystelling van teenliggaampies en proteïene in OM DIE WERK TE DOEN
  • Dit sluit ook die verhoogde bloed toevloei in
  • Dit is ‘n proses wat ure en selfs dae kan neem.

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Kroniese Inflammasie vind plaas wanneer die immuunrespons nie end kry nie en aanhou hinder. Wat oor tyd onnodige skade kan veroorsaak op organe en ander weefsel.

Simptome van Kroniese Inflammasie

Onderstaande skete en pyne kan vir maande en weke aangaan

  • Totale lusteloosheid en moegheid
  • Koors
  • Mondsere
  • Rash
  • Abdominale pyne
  • Borspyne

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Wat veroorsaak Kroniese Inflammasie

Kroniese Inflammasie het verskeie agente of oorsake

Dit kan wees;

  • Akute inflammasie wat onderdruk word of onbehandeld gelaat word
  • Infeksie of ou beserings
  • Outo-immuun oorsake wat gesonde weefsel of organe aanval
  • Langtermyn blootstelling aan chemiese stowwe, giftige gasse soos asbes, fabrieksrook, petrochemiese produkte en vuil lug en water.

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Neem kennis dat almal nie Kroniese Inflammasie weens bogenoemde ontwikkel nie.

  • Kroniese inflammasie het nie altyd ‘n duidelike bewysbare oorsaak nie.
  • Kan genetiese faktore ook wees
  • Die Literatuur verwys na enkele oorsake wat kroniese inflammasie bevorder.

inflammation-diagram

Watter Impak het Kroniese Inflammasie en Stres op die Liggaam

Met kroniese inflammasie (stres) kan die liggaam se immuunrespons (wat inflammasie is wat ontstaan) gesonde selle, weefsel en organe beskadig.

Dit kan as dit nie behandel word nie, oor tyd, weefsel laat afsterwe, DNA beskadig en ook interne weefselskade of “scars” veroorsaak weens die geïnflammeerde toestand van die weefsel.

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Kroniese Inflammasie word verbind aan vele siektetoestande

Dit is;

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Hoe word Kroniese Inflammasie Bestuur?

  • Inflammasie word verkeerd gesien en gelees. Dit is ‘n natuurlike proses en deel van die immuunstelsel se heling en gesond word proses.
  • Wanneer inflammasie kronies word, is dit belangrik om dit onder beheer te kry. Inflammasie kan langtermyn skade veroorsaak.

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Daar is medikasie beskikbaar by dokters en apteke.

Kidney

Pierre @ Ecohealth verkies om van natuurlike produkte te bevorder as moontlike hulpmiddels.

Kruie word in die media baie verdag gemaak as hulpmiddel en voeding vir mense, veral wanneer hul teenoor medikasie afgespeel word.

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  • Niemand ontken die wonder en rol van medikasie nie. Maar medikasie is vir siek mense en is dus “Sick Care” en is net vir tydelike gebruik.
  • Daar is baie vergelykende studies van medikasie teenoor kruie en kragtige kruie soos kankerbos, gemmer, borrie, peper, komyn, kaneel en andere kruie presteer in vele gevalle ewe goed en selfs beter.
  • Maar dit is nie Pierre @ Ecohealth se geveg of ons doel nie.
  • Pierre @Ecohealth is in voorkomende gesondheid en gesonde leefwyses en style. Met produkte wat elke dag as voedselaanvuller gebruik kan word. Wat al die eienskappe bevind en, inflammasie nog voordat dit voorkom, sal beveg.

Lees hier oor kruie wat bekend is dat dit Inflammasie beveg.

Hierdie kruie word in kombinasie saamgestel. Sodat mens spesifieke toestande soos artritis

Health benefits of dietary fibres 2

Pyn en Inflammasie I

Inleiding

Inflammasie is ‘n natuurlike reaksie van die immuunstelsel om skade wat toksienes en ander skadelike mikrobe te verhoed.

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Hierdie natuurlike reaksie van die immuunstelsel poog om;

  • die “skadelike agent” of vreemde organismes en hul skadelike vermoëns te neutraliseer, te dood, uit te skakel of te beperk.
  • In dieselfde aksie, om die proses van “sel herstel” of selfs “tissue repair” te begin.

inflammation-diagram

Inflammasie, as proses kan;

  1. Akuut beskou word, wat ‘n kort tydelike tydperk verteenwoordig van minute tot enkele dae. Dit gaan gewoonlik gepaard met vloeistof in die beseerde plek, asook bepaalde tipes van immuunselle betrokke en neutrofiele.
  2. Kroniese inflammasie gaan gepaard met die versameling van limfosiete en monosiete. Gaan ook gepaard met vaskulêre proliferasie en fibrose. (Verlies van mobiliteit en misvormde gewrigte)

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Die funksie van Neutrofiele

Neutrofiele is mees algemene witbloedsel in die menslike liggaam. Die funksie van neutrofiele by inflammasie volg in ‘n proses van stappe.

  • Die neutrofiele of selle moet eers deur die bloedstroom migreer na waar die inflammasie of ontsteking is.
  • Hierdie beweging van molekules of selle word bestuur deur sekere proteïene in die bloedstroom
  • Wat lei na bepaalde uitdrukking van merkers op die reseptore op die seloppervlakte.
  • Neutrofiele by die plek van inflammasie, vreet/ vernietig/absorbeer die vreemde organisme deur die vrylating van baie kragtige geaktiveerde ensieme wat uit suurstof genereer is.
  • Sou die partikel of organisme te groot wees vir die neutrofiel, vind die proses nog steeds plaas
  • Behalwe dat die kragtige ensieme van die neutrofiel die organisme van die buitekant sou aanval
  • Vir die rede dat daar weefselverlies of skending is wat met infeksies gepaardgaan.

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Gedurende hierdie proses

Word ander selle, limfosiete en monosiete tot die proses ontplooi.

Antibiotika Reaksie

Allergy_to_Antibiotic_Cefaclor

Monosiete aktiveer

  • inflammatoriese eienskappe om meer effektief te wees in die “opruimingsproses” van die wond, wanneer dit normaliseer.
  • Monosiete het ook ander verreikende fisiologiese eienskappe. Nie net op die plek waar die inflammasie voorkom nie, maar ook op ander plekke in die liggaam wat kan veroorsaak dat inflammasie vererger.
  • ‘n Hoë telling van monosiete in jou bloedstroom, kan beteken dat jou liggaam ‘n infeksie kan beveg.
  • Lae telling van monosiete in jou bloed, kan weer beteken dat die liggaam moontlik aan ‘n vitamientekorte kan ly. Of dat ʼn persoon anemies is, of hoë stresvlakke ervaar.

inflammation

  • Monosiettellings kan ook ander fisiologiese effekte meebring, soos die onttrekking van kalsium in die bene, abnormale vorming van teenliggaampies en die vrystelling van B-selle in die bloedstroom.
  • Sou die faktore wat vrygestel word van monosiete in die bloedstroom ongekontroleerd hul gang gaan, kan daar langtermyn gevolge wees vir ‘n persoon se gesondheid.
  • Neutrofiele sowel as monosiete kan by ‘n besering suurstof molekules vrystel wat kan lei tot oksidering of “oxidative burst”
  • Dit sou die bestaan van kroniese inflammasie vir iemand beteken.
  • En die gebruik van kroniese medikasie om dit te onderdruk.

Dit is hier waar Pierre @ Ecohealth ‘n keuse van bekende natuurlike middels gebruik om inflammasie op ʼn natuurlike manier te beheer en of te onderdruk.

mitochondrial-oxidative

 

Pierre @ Ecohealth Kruiemiddels uitkomste

  • Vermindering van pyne en kroniese pyn
  • Vermindering van inflammasie
  • Inhibering van gewrigvernietigende prosesse
  • Voorkoming van oksidasie stres en vrye radikale se invloed by weefsel